Depression and Anxiety Trial, Not Yet Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- Adults aged 18 to 65 years (inclusive), of any gender, and of Han Chinese ethnicity.
- People who have been diagnosed with a depressive disorder based on a specific set of recognised diagnostic guidelines (DSM-IV), confirmed through a structured psychiatric interview.
- People who are being treated as outpatients or inpatients, have a depression severity score of 17 or higher on a standard rating scale (HAMD-17), score 13 or lower on a scale used to check for signs of hypomania (HCL-32), and score 4 or higher on a standard measure of overall illness severity (CGI-S).
- People experiencing their first depressive episode, where symptoms have lasted no longer than 3 months, and who have not taken antidepressants or other psychiatric medications in the past 3 months.
- People who have provided written consent to take part in the trial.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who also meet the diagnostic criteria for other mental health conditions under the same diagnostic guidelines, such as schizophrenia, bipolar disorder, or obsessive-compulsive disorder, among others.
- People with an intellectual disability, those who are unable to cooperate with the trial for any reason, or those who did not have full legal decision-making capacity at the time their illness began.
- People who have a neurological or brain-related condition (such as stroke, brain bleed, brain tumour, Parkinson's disease, or epilepsy), or a history of severe traumatic brain injury.
- People who have attempted suicide in the past 3 months, or who are currently assessed as being at high suicide risk based on a specific item on a standard rating scale (MADRS item 10 score of 5 or higher).
- People who are pregnant or breastfeeding, unable to use reliable contraception during the study, or who plan to become pregnant or father a child within 3 months of the study starting.
- People with a known allergy to the study medication (escitalopram oxalate) or any of its ingredients.
- People who are currently taking other medications that could interfere with assessing how well the study medication works.
- People who have taken part in another drug clinical trial within the past 3 months.
- People who have a reason they cannot safely undergo MRI scanning, such as having metal implants in their body or experiencing claustrophobia.
- People whom the trial investigators consider unsuitable for participation for any other reason.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
If you need support right now
This page includes language about suicide and self-harm, because that is how the trial's eligibility criteria are written. If reading it has been hard, you do not have to keep going. The services below are free, confidential, and answered by people trained for exactly this.
If you or someone else is in immediate danger, call 000.
- Lifeline — 24/7 crisis support: 13 11 14
- Suicide Call Back Service — 24/7 counselling: 1300 659 467
- 13YARN — 24/7, for Aboriginal and Torres Strait Islander people: 13 92 76
- Beyond Blue — 24/7 mental health support: 1300 22 4636
- Kids Helpline — 24/7, free and private for anyone aged 5 to 25: 1800 55 1800
- headspace — mental health support for 12 to 25 year olds: headspace.org.au
- Emergency: 000
Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention. If you are in immediate danger, call your local emergency number.
Voxsanity is not a crisis service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.
Contact this trial
Phone: 86-010-82805307
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change from baseline in Hamilton Depression Rating Scale (HAMD)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 31 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.