Heart Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Healthy adults aged 18–35 years, without any known acute or chronic illness, who are non-smokers, have a body mass index (BMI) between 20 and 24.9, and have a negative result on a standing blood pressure test (orthostatic test)
- Adults aged 60 or older who have high blood pressure (hypertension) and are being monitored at a hypertension clinic
- People with controlled high blood pressure and a negative standing blood pressure test, who do not have diabetes
- People with controlled high blood pressure who show a drop in blood pressure when standing up (orthostatic hypotension), confirmed by a standing blood pressure test
- People with controlled high blood pressure who show a rise in blood pressure when standing up, confirmed by a standing blood pressure test
- People with controlled high blood pressure and diabetes, who have not previously been diagnosed with nerve-related problems affecting automatic body functions (autonomic dysfunction)
- People who are able to read, understand, and sign a written consent form
Who may not be able to join:
- People with dementia, a brain or nerve degenerative condition, or any cognitive impairment that would prevent them from understanding what the study involves
- People with known heart or blood vessel disease, including heart failure of a certain severity, a heart attack in the past 6 months, significant irregular heartbeat, or blocked arteries in the limbs
- People whose high blood pressure is not currently under control
- People who have had a change to their blood pressure medications within the past 4 weeks
- People who have a cardiac pacemaker fitted
- People currently taking certain heart rhythm medications (class I, III, or IV antiarrhythmics), digoxin, alpha-blocker medications, or other drugs known to significantly affect how the heart's automatic nervous system functions
- People with severely reduced kidney function or severe liver failure (confirm with trial site for specific test thresholds)
- People with an active cancer diagnosis
- People with a BMI of 35 or above
- People who have had an acute illness within the past 4 weeks
- People who currently smoke
- People who are unable to safely ride a stationary exercise bike for testing purposes
- People with severe psychiatric conditions that are not currently stable with treatment
- People who are pregnant or breastfeeding
- People who are already participating in another clinical study
- People who are unwilling or unable to provide written consent
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Amela Kabaklić, MD, PhD, University Medical Centre Ljubljana
Phone: +386 1 522 43 05
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Heart Rate Variability
Can't join this trial?
Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.