Breast Cancer Trial, By Invitation
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- Women between 18 and 75 years of age.
- People who have been confirmed through a tissue sample (biopsy) to have invasive breast cancer that has spread to the lungs, diagnosed using specialised scans such as a CT, PET-CT, or MRI.
- People whose cancer has continued to grow or spread after receiving at least one course of chemotherapy-based treatment for advanced or returning breast cancer.
- People who have at least one measurable tumour spot in the lung (at least 10 mm in size on a scan) that has not previously been treated with radiotherapy.
- People whose heart, liver, kidneys, and blood are functioning at adequate levels, as confirmed by blood tests and a heart tracing (ECG) (confirm with trial site for specific values).
- People who are generally able to carry out basic daily activities (rated 0–2 on a standard medical scale) and who are expected to live for at least 3 months.
- Women who could become pregnant must agree to use medically approved contraception during treatment and for at least 3 months after the last treatment dose.
- People who are willing to take part voluntarily, sign a consent form, and follow the treatment and follow-up schedule.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who have had radiotherapy (other than palliative radiotherapy) within the 3 weeks before starting the trial, or major surgery within the 3 weeks before the first treatment cycle (minor procedures such as fitting a vascular access port are generally not included in this restriction — confirm with trial site).
- People who are still experiencing side effects rated moderate or worse from previous treatments such as chemotherapy or surgery (hair loss and certain other conditions may be exceptions — confirm with trial site).
- People with a significant or poorly controlled heart condition, including heart failure, angina, a heart attack within the past 6 months, or serious irregular heart rhythms.
- People who have a build-up of fluid in body cavities (such as the chest or abdomen) that cannot be managed by draining or other methods.
- People with an active hepatitis B or hepatitis C infection, with abnormal liver function results.
- People who are currently pregnant or breastfeeding.
- People with a history of severe allergic reactions, or a known allergy to any of the standard medications used in this trial, or to any equipment or gases used in hyperbaric oxygen therapy (HBOT), such as pure oxygen.
- People who have medical conditions that make hyperbaric oxygen therapy (a treatment involving breathing pure oxygen in a pressurised chamber) unsafe, such as an untreated collapsed lung (pneumothorax), large air pockets in the lungs (pulmonary bullae), severe emphysema, a history of epilepsy with seizures in the past 2 years, or a current severe flare-up of sinus or ear infection.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
If this is close to home
This page includes language about advanced illness, prognosis, or palliative care, because that is how the trial's eligibility criteria are written. Seeing it set out plainly can land hard, whether it is about you or about someone you are caring for. You do not have to be at a crisis point to talk to someone.
- Griefline — grief and loss counselling, 9am to 6pm weekdays and midday to 6pm weekends (AEST/AEDT): 1300 845 745
- Carer Gateway — practical and emotional support if you are caring for someone, 8am to 5pm weekdays: 1800 422 737
- Canteen — for 12 to 25 year olds affected by cancer, their own or a family member's: 1800 945 215
- Palliative Care Australia — directory of palliative care services near you: palliativecare.org.au
- Lifeline — 24/7, for any kind of distress, at any hour the services above are closed: 13 11 14
Palliative care is not the same as giving up on treatment, and it is not only for the last weeks of life. It is symptom and comfort care that can run alongside active treatment, including a clinical trial.
Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of support and crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention.
Voxsanity is not a counselling or medical service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
This date has passed while the registry still lists the trial as open to participants. Sponsors often update a trial's status without revising its projected end date, so it may well still be recruiting — but the record is out of date in at least one respect. Check with the study contact before relying on either.
Where this trial is recruiting
Primary endpoints
Objective Response Rate
Can't join this trial?
Data last synced from ClinicalTrials.gov: 29 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.