Depression and Anxiety Trial, Not Yet Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- People who are older than 60 years of age.
- People who show signs of difficulty with executive functions (such as planning, organising, or attention), either through self-reported problems on standardised questionnaires or through results on cognitive performance tests.
- People who have a diagnosis of a depressive disorder — such as Major Depressive Disorder or Persistent Depressive Disorder — either currently or within the last 3 years, confirmed through a structured clinical interview.
- People who have experienced two or more depressive episodes across their lifetime, meaning their depression is considered recurrent.
- People who are either currently taking antidepressant medication on a stable dose for at least 6 weeks, or who are not taking any antidepressant medication, with no plans to change this during the study.
- People who are fluent in English.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who have other psychiatric conditions identified through a structured clinical interview, including a history of bipolar disorder or psychosis (note: having an anxiety disorder alongside depression does not automatically exclude someone — confirm with trial site).
- People whose depression is currently severe, based on a specific rating scale score (confirm with trial site).
- People who are assessed as having acute suicidal thoughts at the time of clinical evaluation.
- People who are experiencing acute grief from a loss that occurred within the past month.
- People who have had a moderate or severe alcohol use disorder or substance use disorder within the last 12 months.
- People who are taking certain medications that could significantly interfere with the study treatment (a specific list of these medications would be reviewed by the trial site).
- People who have a primary neurological condition, such as epilepsy, a brain tumour, Parkinson's disease, Alzheimer's disease, or another dementia diagnosis.
- People who score below 23 on the Montreal Cognitive Assessment, which is a standard memory and thinking test.
- People whose main cognitive difficulty is with memory, rather than other areas of thinking, based on test results or a clinician's judgement.
- People with a physical or intellectual disability that would affect their ability to complete the study assessments.
- People with an unstable medical condition that requires urgent treatment.
- People who have conditions or implants that make MRI scanning unsafe (confirm with trial site for full details).
- People who have received electroconvulsive therapy (ECT) or transcranial magnetic stimulation (TMS) within the last 2 months.
- People who are currently receiving psychotherapy.
- People who are currently taking part in other research studies, particularly those involving brain stimulation (such as TMS or tDCS) or investigational drugs (observational studies that involve no intervention are generally acceptable — confirm with trial site).
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
If you need support right now
This page includes language about suicide and self-harm, because that is how the trial's eligibility criteria are written. If reading it has been hard, you do not have to keep going. The services below are free, confidential, and answered by people trained for exactly this.
If you or someone else is in immediate danger, call 000.
- Lifeline — 24/7 crisis support: 13 11 14
- Suicide Call Back Service — 24/7 counselling: 1300 659 467
- 13YARN — 24/7, for Aboriginal and Torres Strait Islander people: 13 92 76
- Beyond Blue — 24/7 mental health support: 1300 22 4636
- Emergency: 000
Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention. If you are in immediate danger, call your local emergency number.
Voxsanity is not a crisis service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.
Contact this trial
Phone: 615-875-0032
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
NIH Examiner; Resting state fMRI functional connectivity
Can't join this trial?
Data last synced from ClinicalTrials.gov: 29 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.