Depression and Anxiety Trial, Recruiting NCT07532551 Sponsor: National University of Singapore Condition: Depression and Anxiety
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Depression and Anxiety Trial, Recruiting

NCT07532551
Recruiting Not Applicable

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People aged 21 years or older
  • People with a moderate level of depression and/or anxiety, based on specific questionnaire scores (known as Tier 2–3)
  • People with a PHQ-9 score (a depression questionnaire) between 5 and 19
  • People with a GAD-7 score (an anxiety questionnaire) between 5 and 14
  • People who are currently or have previously been involved in delivering, supervising, or running the internet-based therapy (iCBT) programme
  • People who have directly supported patients enrolled in this study
  • People who are able to give their informed consent to participate

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who are unable to read or understand English at approximately a Primary 6 level
  • People who are unable to use the internet, whether due to lack of access or not having enough digital skills
  • People who do not own a mobile device or are unable to use the therapy app on a device
  • People who are currently experiencing psychosis
  • People who are suspected of having a personality disorder
  • People whose main concern is obsessive compulsive disorder (OCD)
  • People with severe depression or anxiety (classified as Tier 4)
  • People with a PHQ-9 score of 20 or above
  • People with a GAD-7 score of 15 or above
  • People with any level of suicidal risk or thoughts of suicide
  • People who score more than 2 on Question 9 of the PHQ-9 questionnaire (which relates to thoughts of self-harm or suicide)
  • Service providers who have had no direct involvement in the iCBT programme
  • Service providers who have managed fewer than one referred case, or have been involved in the programme for less than one month at the time of recruitment
  • People whose participation could create pressure on others or introduce bias, such as those in a supervisory role over other potential participants
  • People who are unable to give their informed consent to participate

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 2 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

If you need support right now

This page includes language about suicide and self-harm, because that is how the trial's eligibility criteria are written. If reading it has been hard, you do not have to keep going. The services below are free, confidential, and answered by people trained for exactly this.

If you or someone else is in immediate danger, call 000.

  • Lifeline — 24/7 crisis support: 13 11 14
  • Suicide Call Back Service — 24/7 counselling: 1300 659 467
  • 13YARN — 24/7, for Aboriginal and Torres Strait Islander people: 13 92 76
  • Beyond Blue — 24/7 mental health support: 1300 22 4636
  • Emergency: 000

Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention. If you are in immediate danger, call your local emergency number.

Voxsanity is not a crisis service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
National University of Singapore
Registry
ClinicalTrials.gov
Start date
1 April 2026
Est. completion
1 March 2028

Where this trial is recruiting

🇸🇬 Singapore

Primary endpoints

Change in the depression scores (PHQ-9) from baseline at: 5 weeks, 8 weeks, 3 months, 6 months; Change in the anxiety scores (GAD-7) from baseline at: 5 weeks, 8 weeks, 3 months, 6 months; Change in the functional scores (WHODAS 2.0) from baseline at: 5 weeks, 8 weeks, 3 months, 6 months

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 2 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov