Alzheimer's Disease Trial, By Invitation NCT07543094 Sponsor: Ruijin Hospital Condition: Alzheimer's Disease
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Alzheimer's Disease Trial, By Invitation

NCT07543094
By Invitation Not Applicable

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who have at least one positive Alzheimer's-related biomarker test result, such as a specific blood test (plasma p-tau217), a brain imaging scan (amyloid PET), or a spinal fluid test showing abnormal protein ratios — as defined by 2024 Alzheimer's Association diagnostic criteria.
  • People aged between 50 and 75 years old (inclusive).
  • People who have completed at least 6 years of formal schooling.
  • People who score 0.5 or 1.0 on a standard memory and thinking assessment called the Clinical Dementia Rating (CDR) — meaning mild cognitive concerns are present (confirm with trial site).
  • People who score 21 or above on a standard thinking and memory test called the MMSE.
  • People who have been taking memory or thinking support medications (such as cholinesterase inhibitors or memantine) at a stable dose for at least 6 weeks before the screening visit.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have, or have previously had, a significant brain or nervous system condition other than Alzheimer's disease — such as epilepsy, stroke, or multiple sclerosis — or who have had brain surgery or a serious head injury.
  • People who are currently taking medications that may significantly affect thinking or memory, such as anti-seizure drugs, antipsychotics, or benzodiazepines.
  • People for whom an MRI scan or the study's brain stimulation device would not be safe — for example, those with certain metal implants, a pacemaker, or severe claustrophobia.
  • People who have significant structural abnormalities in the brain shown on an MRI scan, such as hydrocephalus, stroke damage, or severe changes to the brain's white matter.
  • People who have been diagnosed with major depression or another active psychiatric condition that is not well controlled.
  • People who have a serious or unstable health condition — such as significant heart, kidney, liver, breathing, or active cancer-related illness — that the trial investigator considers a safety risk, or people with a history of alcohol or substance dependence.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Trial details

Status
By Invitation
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
1 November 2025
Est. completion
30 September 2027

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Changes in Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog 11) Score

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov