Printed from Voxsanity (voxsanity.com.au) — NCT07560475 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.
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Phase 2 Breast Cancer Trial, Not Yet Recruiting
NCT07560475
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- Adults aged 18 years or older.
- People with advanced breast cancer that has been confirmed by laboratory testing to be HER2-positive (meaning the cancer cells have high levels of a particular protein that drives cancer growth).
- People with advanced breast cancer who have received no more than 2 previous rounds of systemic treatment (such as chemotherapy or targeted therapy given throughout the body).
- People with an expected survival time of at least 4 months.
- People who have at least one tumour that can be measured using specific scanning methods (confirm with trial site for exact size requirements).
- People whose major organs (such as liver, kidneys, and bone marrow) are working well enough without needing blood transfusions.
- People who are willing to take part voluntarily, sign a consent form, follow the trial requirements, and attend follow-up visits.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who have previously been treated with a type of cancer drug called an anti-HER2 antibody-drug conjugate (ADC).
- People who have cancer that has spread to the membranes surrounding the brain or spinal cord, or who have active cancer spread in the brain.
- People who have had another type of cancer in the past 5 years, with some exceptions for certain fully treated skin cancers and cervical conditions, or cancers treated only with surgery more than 5 years ago (confirm with trial site).
- People who have had major surgery or a serious injury within the 4 weeks before joining, or who have major surgery planned during the trial.
- People who have taken part in another clinical drug trial within the 4 weeks before joining.
- People who have an inherited tendency to bleed or a disorder affecting blood clotting.
- People with high blood pressure that remains above a certain level (140/90 mmHg) even with standard blood pressure medication.
- People with a history of significant lung conditions, such as lung scarring, active lung inflammation, or radiation-related lung damage that has required treatment.
- People with serious heart conditions, including moderate-to-severe heart failure, unstable chest pain, a heart attack within the past year, or irregular heart rhythms that have needed medical treatment.
- People with conditions that make it difficult to swallow, absorb, or digest medication, such as trouble swallowing, ongoing severe diarrhoea, or a bowel blockage.
- People who are known to be allergic to any ingredient in the trial drugs.
- People with fluid build-up around the lungs or in the abdomen that cannot be controlled by draining or other medical treatments.
- People with serious uncontrolled health conditions, including immune system disorders (such as HIV), a history of organ transplant, active hepatitis B or C, or a serious ongoing infection requiring treatment.
- People whom the trial investigators consider unsuitable for any other reason.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Status
Not Yet Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
10 June 2026
Est. completion
31 December 2028
Where this trial is recruiting
🇨🇳 China
Primary endpoints
Objective Response Rate (ORR)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.
Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.