Sleep Disorders Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who can read and understand study materials written in English, confirmed by a standard reading test score above 85
• People who score 18 or higher on a depression symptom questionnaire (called the MADRS-S) during the screening process
• People who have been diagnosed with Major Depressive Disorder (a serious form of depression) confirmed by a clinician interview
• People who are taking antidepressant medication only if their dose has stayed the same for at least 30 days before the screening period
• People who have either a local doctor or healthcare provider responsible for their ongoing care and available to be contacted if needed, or who have confirmed knowledge of local support resources
• People who are able to give informed consent and follow the study procedures
• People who have access to a quiet space at home suitable for brain stimulation sessions

Who may not be able to join:

• People with a significant ongoing medical condition that, in the opinion of the study clinician, could interfere with participation, safety, or the study results
• People with a current or past diagnosis of bipolar disorder or a psychotic disorder, or who have had an alcohol or substance use disorder in the past 6 months, as determined during the screening interview
• People with serious thoughts of suicide or suicidal behaviour, based on clinician assessment and a formal rating scale
• People who have used prescription or over-the-counter sleep medications, or started a sleep-focused therapy programme, in the 30 days before screening
• People with a history of seizures or epilepsy
• People who have an active implanted medical device located above the neck (such as a deep brain stimulator or cochlear implant), or metal implants in the head or neck area that are not compatible with MRI
• People who are currently using any prescription or over-the-counter sleep medications, or are actively taking part in any treatment specifically aimed at improving sleep
• People who are currently pregnant, planning to become pregnant during the study, or who are breastfeeding — people who could become pregnant would be required to use an accepted form of contraception throughout the study (confirm with trial site for full details)

Important: Always verify eligibility with the trial site directly before applying.