Phase 2 Cardiomyopathy Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are 18 years of age or older and are able to give their own consent to participate
- People who have been clinically diagnosed with a type of heart muscle disease called dilated cardiomyopathy (DCM) caused by a change in the LMNA gene, where the left side of the heart is not pumping properly
- People whose LMNA gene mutation has been confirmed as harmful or likely harmful by an approved, accredited genetic testing laboratory
- People whose heart failure symptoms fall into a mild-to-moderate range (classified as NYHA Class I, II, or III — confirm with trial site if unsure which class applies)
- People whose heart pumping function, measured by an ultrasound of the heart, falls within a specific range (confirm with trial site for exact values)
- People who have had a heart device fitted (either an ICD or CRT-D, which are devices that monitor and correct dangerous heart rhythms) for more than 3 months before joining the trial
Who may not be able to join:
- People with any long-term medical condition that the trial doctors believe could put them at risk or make it difficult to take part safely
- People who were admitted to hospital in the 3 months before signing up for any of the following: heart failure, serious heart rhythm problems that needed external electric shock treatment, or repeated shocks from their implanted heart device
- People who have needed, or are expected to need, a mechanical heart pump device or a heart transplant due to severe heart failure
- People who currently need, or are expected to need, heart-strengthening medication given continuously through a drip (IV)
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Safety: Frequency, severity, and relatedness of treatment-emergent adverse events (TEAEs)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.