Phase 2 Depression and Anxiety Trial, Not Yet Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- People who are able to understand the study procedures and are willing to give written consent to participate (or whose legal guardian can give consent on their behalf)
- People aged 14 years or older, of any sex
- People who have previously received an allogeneic hematopoietic stem cell transplant (a transplant using stem cells from a donor)
- People who have been newly diagnosed with depression following their stem cell transplant, confirmed using standardised assessment tools
- People who show evidence that their transplanted cells have successfully started producing white blood cells before entering the trial
- People who are willing and able to follow all study procedures and attend follow-up appointments
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who do not wish to take part in the study
- People who have a severe psychiatric disorder or a severe physical symptom disorder
- People who have a known allergy to Xiaochaihu Granules or any ingredient in that medicine
- People who are currently taking other antidepressant medicines
- People with severe organ problems or an unstable medical condition, including an uncontrolled bloodstream infection or a life expectancy of less than 3 months
- People who have had their spleen removed
- People with significant kidney problems, where a specific blood test (serum creatinine) measures at or above 2.0 mg/dL
- People with a cholestatic liver disease or an unresolved liver condition related to their transplant called hepatic veno-occlusive disease
- People with certain serious heart conditions, including unstable chest pain, a heart attack within the past 6 months, severe heart failure (NYHA class III–IV), circulatory failure needing medication to support blood pressure or heart function, or a clinically significant irregular heartbeat requiring treatment
- People with severe breathing difficulties requiring a breathing machine or very high levels of oxygen support (50% or more)
- People whose original disease is considered to be in complete remission following their transplant, as defined by the study protocol (confirm with trial site)
- People who have taken part in another interventional clinical trial within the past 21 days, or within 5 half-lives of any investigational medicine used in that trial, whichever period is longer
- People who have any other condition that the trial doctor considers would make participation unsuitable
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
If this is close to home
This page includes language about advanced illness, prognosis, or palliative care, because that is how the trial's eligibility criteria are written. Seeing it set out plainly can land hard, whether it is about you or about someone you are caring for. You do not have to be at a crisis point to talk to someone.
- Griefline — grief and loss counselling, 9am to 6pm weekdays and midday to 6pm weekends (AEST/AEDT): 1300 845 745
- Carer Gateway — practical and emotional support if you are caring for someone, 8am to 5pm weekdays: 1800 422 737
- Canteen — for 12 to 25 year olds affected by cancer, their own or a family member's: 1800 945 215
- Palliative Care Australia — directory of palliative care services near you: palliativecare.org.au
- Lifeline — 24/7, for any kind of distress, at any hour the services above are closed: 13 11 14
Palliative care is not the same as giving up on treatment, and it is not only for the last weeks of life. It is symptom and comfort care that can run alongside active treatment, including a clinical trial.
Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of support and crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention.
Voxsanity is not a counselling or medical service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Primary endpoints
Change in Hospital Anxiety and Depression Scale (HADS) score; Change in Hamilton Depression Rating Scale (HAMD) score; Change in Traditional Chinese Medicine (TCM) syndrome score
Can't join this trial?
Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.