Phase 2 Hearing Loss Trial, Recruiting NCT07637981 Sponsor: Dendrogenix Condition: Hearing Loss
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Phase 2 Hearing Loss Trial, Recruiting

NCT07637981
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have noticed difficulty hearing in noisy environments, lasting at least 6 months before the screening appointment
  • People who show a measurable difficulty understanding speech when there is background noise, in at least one ear
  • People whose hearing test results fall within the normal range or show up to a moderately severe level of hearing loss

Who may not be able to join:

  • People who currently have a hole or tear in their eardrum
  • People who currently have an ear infection, whether recent or ongoing
  • People whose hearing loss is caused by a genetic condition
  • People with severe hearing loss, whether it affects both ears equally or unevenly
  • People who are currently receiving any treatment known to damage hearing
  • People who had a middle or outer ear infection that cleared up fewer than 7 days before the start of the trial
  • People with a history of long-term inflammatory or infected ear disease, or a condition called cholesteatoma (a skin growth in the ear)
  • People with a history of otosclerosis, suspected fluid leak in the inner ear, suspected damage to the inner ear membrane, or ear injury caused by pressure changes (confirm with trial site)
  • People who have had any type of ear surgery in the past
  • People whose hearing loss comes and goes over time
  • People whose hearing loss is caused by a physical blockage or structural problem in the ear (known as conductive hearing loss)
  • People with a history of Ménière's disease, autoimmune-related hearing loss, radiation-caused hearing loss, or a non-cancerous tumour on the hearing nerve (acoustic neuroma)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

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Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Dendrogenix
Registry
ClinicalTrials.gov
Start date
13 May 2026
Est. completion
1 October 2027

Where this trial is recruiting

🇧🇪 Belgium

Primary endpoints

Safety and tolerability: incidence, nature, severity and causality of treatment emergent adverse events (TEAE) and (Serious) Adverse events (S)(AEs); Tolerability at the injection sites using a 1-5 scale Common Terminology Criteria for Adverse Events (CTCAE) for pain, erythema, swelling, induration, nodule and ulceration with 1 : normal and 5: worst possible symptom/sign; Number of participants with at least one clinically significant abnormal laboratory result; Number of Participants With Abnormal ECG Findings

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov