Heart Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Adults aged 18 or older who have been admitted to a cardiac intensive care unit and need a breathing machine (mechanical ventilator) for more than 12 hours

The trial also includes specific subgroups for additional research questions. These include people with:

• A serious heart condition called cardiogenic shock (classified as SCAI Stages C, D, or E — confirm with trial site for details)
• Use of a mechanical heart support device, such as an intra-aortic balloon pump or a small pump inserted into the heart (such as an Impella device)
• A weakened heart where the heart is pumping less effectively than normal (ejection fraction below 40%)
• Moderate to severe problems with the right side of the heart not pumping well enough
• Moderate to severe high blood pressure in the lungs (pulmonary hypertension), as defined by major cardiology guidelines

Who may not be able to join:

• People whose breathing machine use is expected to last less than 12 hours
• People with severe chronic lung disease (severe COPD), an abnormal connection between the airways and chest cavity (bronchopleural fistula), or a severe form of lung failure called ARDS (confirm with trial site for technical details)
• People who already use a breathing machine at home or have a permanent breathing tube in their throat (chronic tracheostomy)
• People who are pregnant, currently incarcerated, or receiving a life-support treatment that circulates blood outside the body (ECMO)

Important: Always verify eligibility with the trial site directly before applying.