Cardiomyopathy Trial, Recruiting NCT07658222 Sponsor: Vanderbilt University Medical Center Condition: Cardiomyopathy
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Cardiomyopathy Trial, Recruiting

NCT07658222
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have cirrhosis (severe liver scarring) that has caused serious complications, such as internal bleeding related to liver pressure, episodes of confusion caused by liver disease, or fluid build-up in the abdomen
  • People whose liver disease is rated as moderately severe or worse, based on standard medical scoring systems used by doctors (MELD 3.0 score of 15 or higher, or Child Pugh Class B or C)
  • People aged 18 years or older
  • People who are already receiving ongoing care at the liver (hepatology) clinics at Vanderbilt University Medical Center or the University of Texas Southwestern
  • People who are willing to follow the study plan and attend required visits
  • People who are able to give written consent to participate

Who may not be able to join:

  • People who have had, or currently have, certain heart conditions — including blocked heart arteries, significant heart valve problems, more than mild fluid around the heart, a protein build-up disorder affecting the heart (cardiac amyloidosis), a heart defect present from birth, a pacemaker, or an implanted heart device to correct dangerous heart rhythms
  • People who have end-stage (very advanced) heart, kidney, or lung disease
  • People who have high blood pressure in the arteries of the lungs (pulmonary arterial hypertension)
  • People experiencing a serious sudden worsening of their liver disease that is also causing two or more other organs in the body to fail at the same time (confirm with trial site)
  • People with advanced liver cancer rated at a late stage using a standard liver cancer staging system (Barcelona Clinic Liver Cancer Stage C or D)
  • People who are currently drinking alcohol, based on what they report or on a blood test that detects recent alcohol use
  • People who are pregnant
  • People who have previously had a procedure called a TIPS (a type of internal shunt placed in the liver to manage complications)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Manhal Izzy, MD, Vanderbilt University Medical Center

Phone: 615-875-6540

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
20 January 2026
Est. completion
30 June 2030

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

All-Cause Mortality

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov