Phase 2 Breast Cancer Trial, Not Yet Recruiting NCT07679269 Sponsor: Novartis Pharmaceuticals Condition: Breast Cancer
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Phase 2 Breast Cancer Trial, Not Yet Recruiting

NCT07679269
Not Yet Recruiting Phase 2

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • The participant (and/or their parent or legal guardian) has signed a consent form agreeing to take part, following local guidelines, before joining this follow-on study.
  • The participant is currently enrolled in an existing Novartis-sponsored study, is receiving alpelisib either alone or combined with other drugs, and has completed all required treatment steps in that original study.
  • The participant's doctor (the Investigator) has determined that the participant is currently benefiting from alpelisib treatment in the original study.
  • The participant has kept up with required visits in the original study and, in the Investigator's opinion, has shown the willingness and ability to follow future visit schedules, treatment plans, and other study requirements.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • The participant permanently stopped taking alpelisib in the original study for any reason, including choosing to withdraw consent.
  • The participant currently has ongoing or unresolved side effects rated Grade 3 or higher, or any ongoing side effects that caused alpelisib dosing to be paused in the original study (though people who otherwise meet all criteria may be considered once side effects have improved enough for dosing to resume, as set out in the original study).
  • The participant's current treatment is already government-approved and covered by their country's health system for their condition (in exceptional cases where it is covered nationally but not for a specific individual, the Novartis Study Team should be contacted).
  • The participant is currently taking part in any other experimental clinical trial besides the original Novartis-sponsored study.
  • The participant is pregnant or currently breastfeeding.
  • Female participants who are able to become pregnant and do not agree to use a highly effective form of contraception, and male participants who do not agree to use a condom and/or a highly effective form of contraception — including avoiding sperm donation and taking steps to prevent a partner being exposed to alpelisib through seminal fluid — for the entire duration of the study and for at least one week after stopping alpelisib (or longer if the original study requires it).
  • Other criteria set by the trial may also apply (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 8 July 2026

Contact this trial

Principal Investigator: Novartis Pharmaceuticals, Novartis Pharmaceuticals

Phone: 1-888-669-6682

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
1 January 2027
Est. completion
27 June 2031

Primary endpoints

Number of participants with Adverse Events (AEs) and Serious Adverse Events (SAEs)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov