Alzheimer's Disease Trial, Not Yet Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- The patient or their legal guardian is willing and able to sign a consent form agreeing to take part
- People aged between 50 and 80 years old (inclusive), of any gender
- People who have been newly diagnosed with Alzheimer's disease with dementia
- People with a score of 24 or below on a standard memory and thinking test called the MMSE
- People whose brain scan (PET imaging) shows a positive result for a protein called beta-amyloid
- People with a score of 17 or below on a standard depression rating scale called the HAMD
- People with a score of 7 or below on a scale called the Hachinski score, which helps distinguish different causes of memory problems
- People who have not received any Alzheimer's-related medication in the past month
- People rated as ASA grade 1, 2, or 3 — a general measure of overall physical health used before procedures (confirm with trial site)
- People with a CDR-SB score between 9.5 and 15.5, which is a measure of how much dementia affects daily life
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who have medical reasons preventing them from having an MRI scan, a specific eye/blood vessel imaging test (ICG angiography), or a PET scan
- People who have medical reasons preventing them from having a lumbar puncture (a procedure to collect fluid from around the spine)
- People with serious heart disease or an unstable heart or circulation condition
- People with serious lung disease, including significant breathing problems, or a lung inflammation in the past 3 months
- People with liver problems where certain liver enzyme levels (AST or ALT) are more than 3 times the normal upper limit
- People with kidney problems where kidney filtering function (GFR) is below 60 mL/min, or who need dialysis or blood purification treatment
- People whose MRI scan shows active or recent brain problems, such as brain infection, a growth or mass in the brain, significant bleeding, or 4 or more small bleeds in certain areas of the brain
- People with a history of bleeding in the brain or a stroke that has left significant lasting neurological problems
- People with blood disorders or problems with blood clotting
- People with abnormal thyroid (a gland in the neck) function
- People with moderate or severe narrowing of blood vessels in the brain or neck that has caused significant lasting neurological problems
- People with severely uncontrolled high blood pressure, where the top number is 180 mmHg or above, or the bottom number is 110 mmHg or above
- People whose condition requires ongoing use of steroid medications throughout the body
- People with dependence on alcohol, narcotics, or other substances
- People with serious infectious diseases, including HIV
- People with severe mental health conditions or who may be at risk of suicide
- People who have had surgery to remove a malignant (cancerous) tumour within the past 3 years
- People who have taken part in another interventional clinical trial in the past 3 months
- People who, in their doctor's judgement, are unlikely to be able to cooperate with or complete the required follow-up visits after the procedure
- People who, in their doctor's judgement, are otherwise unsuitable for this trial for any reason
- People who have received a specific type of Alzheimer's treatment called anti-Aβ monoclonal antibody therapy within the past 6 months
- People who have previously had surgery on their neck
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
If you need support right now
This page includes language about suicide and self-harm, because that is how the trial's eligibility criteria are written. If reading it has been hard, you do not have to keep going. The services below are free, confidential, and answered by people trained for exactly this.
If you or someone else is in immediate danger, call 000.
- Lifeline — 24/7 crisis support: 13 11 14
- Suicide Call Back Service — 24/7 counselling: 1300 659 467
- 13YARN — 24/7, for Aboriginal and Torres Strait Islander people: 13 92 76
- Beyond Blue — 24/7 mental health support: 1300 22 4636
- Emergency: 000
Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention. If you are in immediate danger, call your local emergency number.
Voxsanity is not a crisis service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.
Contact this trial
Phone: +86 13061775858
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change From Baseline in Clinical Dementia Rating-Sum of Boxes Score at Month 12
Can't join this trial?
Data last synced from ClinicalTrials.gov: 14 August 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.