Chronic Rhinosinusitis Trial, Recruiting NCT07681973 Sponsor: The Cleveland Clinic Condition: Chronic Rhinosinusitis
Back to Chronic Rhinosinusitis

Chronic Rhinosinusitis Trial, Recruiting

NCT07681973
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must be under 18 years old
  • You must be attending a nose and sinus specialist clinic with a condition called chronic rhinosinusitis (long-term inflammation of the sinuses) along with nasal polyps (small, non-cancerous growths inside the nose)
  • You must have a reduced or lost sense of smell for any reason, except if it was caused by an injury or a tumour

Who may not be able to join:

  • Anyone who is 18 years of age or older
  • People who have nasal polyps on only one side of the nose
  • People who have an autoimmune disease (a condition where the immune system attacks the body's own tissues) (confirm with trial site)
  • People who have a condition that affects how tiny hair-like structures in the airways work, such as Primary Ciliary Dyskinesia (confirm with trial site)
  • People who have cystic fibrosis (an inherited condition affecting the lungs and digestive system)
  • People whose loss of smell was caused by a tumour or a physical injury

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Mohamad Chaaban, MD, The Cleveland Clinic

Phone: 4405062611

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
9 December 2025
Est. completion
31 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Primary Outcome Measure 1: Baseline olfactory function measured by UPSIT score; Primary Outcome Measure 2: Baseline quality-of-life impact of olfactory dysfunction measured by QOD-NS score; Primary Outcome Measure 3: Baseline cognitive function measured by MMSE score; Primary Outcome Measure 4: Baseline nasal cytokine concentration

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov