Alzheimer's Disease Trial, Not Yet Recruiting NCT07708675 Sponsor: MMI (Medical Microinstruments, Inc.) Condition: Alzheimer's Disease
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Alzheimer's Disease Trial, Not Yet Recruiting

NCT07708675
Not Yet Recruiting Not Applicable

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People aged 50 to 79 years old.
  • People who have been diagnosed with highly probable or probable Alzheimer's disease, confirmed using recognised international criteria, along with a positive Alzheimer's biomarker test result.
  • People who score 18 or higher on a standard memory and thinking test called the MMSE.
  • People who the treating doctor considers suitable for a type of lymphatic surgery performed with a robotic-assisted microsurgical system.
  • People who are capable of becoming pregnant must agree to use an accepted form of contraception during the study.
  • People (or their legally authorised representative) who have given written consent to participate, attend all follow-up visits, and complete all required study procedures.
  • People whose intraoperative imaging (imaging taken during surgery) confirms that suitable lymphatic nodes or vessels are present for reconstruction.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People (or their legally authorised representative) who are unwilling to provide written informed consent.
  • People whose dementia is suspected to be a type other than Alzheimer's disease, such as Lewy body dementia, frontotemporal dementia, or vascular dementia.
  • People who have a history of radiation exposure to the head and neck area.
  • People with severe kidney disease (confirm with trial site for specific test values).
  • People with acute (sudden onset) kidney injury.
  • People with an active, serious infection currently being treated with intravenous antibiotics.
  • People who score more than 4 on a disability scale called the modified Rankin Score.
  • People with a significant diagnosed condition affecting the heart, digestive system, breathing, hormones, or nervous system, untreated sleep apnea, a history of mental health disorders, or other conditions that the treating doctor believes could affect safety or study results.
  • People with a known history of significant bleeding problems, clotting disorders, or a condition called Von Willebrand's disease.
  • People who currently have an active cancer diagnosis or who have received cancer treatment within the past 6 months.
  • People who are currently receiving, or have received within the past 6 months, a type of Alzheimer's treatment known as anti-amyloid-beta monoclonal antibody therapy.
  • People who have a medical reason they cannot have an MRI scan.
  • People who are currently enrolled in another clinical research study that the treating doctor believes could affect safety or study results.
  • People who the treating doctor considers ineligible for any other reason.
  • People in whom a condition is discovered during surgery that, in the treating doctor's opinion, would make continued participation not in the person's best interest.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 18 August 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 8336646276

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Not Applicable
Sponsor
MMI (Medical Microinstruments, Inc.)
Registry
ClinicalTrials.gov
Start date
1 October 2026
Est. completion
1 April 2028

Primary endpoints

Device-related serious adverse events at 30-days

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 18 August 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov