Phase 2 Chronic Rhinosinusitis Trial, Recruiting NCT07714525 Sponsor: Deraya University Condition: Chronic Rhinosinusitis
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Phase 2 Chronic Rhinosinusitis Trial, Recruiting

NCT07714525
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults between 18 and 60 years of age.
  • People who are scheduled to have one of the following sinus procedures: functional endoscopic sinus surgery, endoscopic turbinoplasty, or endoscopic septoplasty.
  • People who have been diagnosed with chronic sinusitis and/or nasal polyps that require surgery.
  • People who are able and willing to sign a written consent form agreeing to take part.
  • People who are able and willing to attend all required appointments and follow the study treatment plan.

Who may not be able to join:

  • People with a known allergy to triamcinolone acetonide (a type of steroid medication).
  • People with a known allergy to any ingredient in the special nanocapsule formula used in the study.
  • People for whom steroid treatment is not medically safe for whole-body use.
  • People who have a severe active infection in the nose or sinuses at the time of joining the trial.
  • People who are pregnant or breastfeeding (confirm with trial site).
  • People with diabetes that is not well controlled, where steroid exposure may be a concern (confirm with trial site).
  • People who have a weakened immune system or are taking medication that suppresses the immune system.
  • People who have recently used steroid medication (by mouth, injection, or nasal spray) within the timeframe set out by the study rules (confirm with trial site for exact timeframe).
  • People who are currently taking part in another clinical trial.
  • People who have a medical or mental health condition that may affect their ability to consent, follow the treatment plan, or attend follow-up visits.
  • People who are unable to complete the required questionnaires or attend all follow-up visits.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Sally Mansour Helmy, Deraya University

Phone: +20 102 692 0921

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Deraya University
Registry
ClinicalTrials.gov
Start date
1 May 2026
Est. completion
1 May 2027

Where this trial is recruiting

🇪🇬 Egypt

Primary endpoints

Change in Lund-Kennedy Endoscopic Score; Change in 22-Item Sinonasal Outcome Test Score (SNOT-22)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov