Rare disease

Castleman Disease

Clinical trials recruiting in Australia for Castleman Disease, a rare disease, as the public registries list them.

Also called: Angiofollicular ganglionic hyperplasia; Angiofollicular lymph hyperplasia; Castleman's disease; Angiofollicular lymph node hyperplasia; Angiofollicular lymphoid hyperplasia; Giant lymph node hyperplasia

Sources: ClinicalTrials.gov, Orphanet Checked: 11 October 2026 Not medical advice

At a glance

1 trial recruiting in Australia

13 trials recruiting overseas

Unknown (Point prevalence, Worldwide, Not yet validated) prevalence

All ages age of onset

11 October 2026 date last checked

Trials in Australia

This Australian count is likely to be on the low side. It counts the trials this site files under this condition; the registry’s own search is broader and also returns closely related conditions, some of which have their own page here. If you are searching widely, check the registry as well — every trial below links to its own record.

  • Recruiting Not a phased study

    Study for people with Castleman Disease

    Where
    • Flinders University, Adelaide — Recruiting
    • University of Adelaide, Adelaide — Recruiting
    Who can join Age child, adult, older adult. Sex Anyone, regardless of sex. Healthy volunteers Not accepted.
    Sponsor University of Siena
    Timeline
    Started 6 August 2020 Today 16 October 2026 Estimated completion 6 August 2026

    Past estimated completion. The registry still lists this trial as open, and the date it gave for finishing has been and gone. Confirm with the official record before you act on it.

    NCT05200715 · Checked 11 October 2026

Trials overseas

13 trials for this disease are open to new participants outside Australia, as ClinicalTrials.gov listed them on 11 October 2026. Voxsanity does not publish a page for any of them; the searches below reach them at the registry.

These overseas counts are likely too high. They come from the registry’s own search, which expands a condition name to related conditions, so some of the trials counted are for a different disease in the same family.

Trials not shown here

Some Australian trials are registered only on the Australian New Zealand Clinical Trials Registry and are not shown here. Search them at Australian Clinical Trials.

Key facts

Inheritance Not applicable
Genes Not recorded
Prevalence Unknown (Point prevalence, Worldwide, Not yet validated)
Age of onset All ages

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Available on https://www.orphadata.com. Used under CC BY 4.0. Source: Orphanet / Orphadata (orphadata.com).

Sources and dates

  • ClinicalTrials.gov – trial records, statuses and site lists
  • Orphanet / Orphadata – prevalence, age of onset, inheritance, genes and alternative names, used under CC BY 4.0
  • ClinicalTrials.gov processing date: 10 July 2025.
  • This page last checked by Voxsanity: 11 October 2026.

Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.

Not medical advice.

Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.

Orphanet citation

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Available on https://www.orphadata.com. Used under CC BY 4.0. Source: Orphanet / Orphadata (orphadata.com). Accessed 20 September 2026.

ORPHA:160

Tell us which conditions matter to you

We use requests to help decide what to add next. Telling us about a condition is not a promise that we will add it, and we cannot say when any condition might appear.