Parkinson's Disease Trial, Not Yet Recruiting NCT04616521 Sponsor: Ruijin Hospital Condition: Parkinson's Disease
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Parkinson's Disease Trial, Not Yet Recruiting

NCT04616521
Not Yet Recruiting Not Applicable

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People who have been diagnosed with idiopathic Parkinson's disease (a form of Parkinson's with no known specific cause) based on recognised international diagnostic guidelines.
  • People who are older than 18 years of age.
  • People whose Parkinson's symptoms improved by more than 24% in a pre-surgery test involving levodopa medication, as measured by a standard movement assessment scale.
  • People whose disease severity, measured on a standard rating scale called the modified Hoehn-Yahr Scale, falls between stage 2 and stage 4 while on their Parkinson's medication.
  • People who have read, understood, and signed a written consent form agreeing to take part in the trial.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have an atypical form of parkinsonism (a condition that looks like Parkinson's disease but has a different underlying cause).
  • People with a history of stroke, brain infection, use of certain antipsychotic medications, or brain scan results showing significant brain shrinkage, small areas of brain damage from blocked blood vessels, or other conditions that could interfere with brain surgery.
  • People with cognitive difficulties, mental health conditions, or other serious health conditions — such as dementia, epilepsy, head trauma, brain tumour, schizophrenia, severe depression, bipolar disorder, or personality disorder — that could affect their ability to complete the study assessments or give informed consent.
  • People who have abnormalities in the specific area of the brain that would be targeted during surgery.
  • People with a significant medical history or health conditions that could increase the risk of complications before or after surgery.
  • People with any other conditions that the trial investigators determine could interfere with the surgery, the follow-up visits, or the interpretation of the study results.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 13817864569

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
1 January 2021
Est. completion
30 November 2029

Primary endpoints

Movement Disorder Society-Sponsored Unified Parkinson's Disease Rating Scale - Part III (MDS UPDRS-III)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov