Parkinson's Disease Trial, By Invitation
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- A person must have been diagnosed with idiopathic Parkinson's disease, meaning Parkinson's that has no known cause, showing at least 2 of the main features: tremor (shaking), rigidity (stiffness), or bradykinesia (slowness of movement).
- A person must be scheduled to have deep brain stimulation (DBS) surgery as a treatment for advanced Parkinson's disease, based on a clinical evaluation.
- A person's Parkinson's motor symptoms, measured by a standard rating scale while off medication, must score above 25, indicating advanced disease.
- A person's symptoms must respond to levodopa (L-dopa) medication, shown by at least a 30% improvement in motor scores when on versus off medication, or the person must have severe tremor that cannot be controlled by medication.
- A person must have ongoing, disabling movement problems or difficult side effects from medications — such as involuntary movements, unpredictable symptom changes, or prolonged periods when medication is not working well — despite receiving the best available medical treatment.
- A person's pre-surgery MRI brain scan must show no signs of certain brain abnormalities, such as adhesions (areas where tissue has stuck together) or abnormal blood vessels (confirm with trial site).
- A person must be willing and able to remain awake and cooperative during the surgical procedure for up to 40 minutes.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who have a medical reason that makes surgery unsafe, including those who have taken blood-thinning or anti-clotting medications within the past week, may not be eligible.
- People who have significant cognitive (thinking or memory) or psychiatric (mental health) problems, as identified through clinical neuropsychological testing, may not be eligible.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Globus pallidus internus local field potentials; Frontal and parietal electrocorticography
Can't join this trial?
Data last synced from ClinicalTrials.gov: 30 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.