Printed from Voxsanity (voxsanity.com.au) — NCT05573542 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.
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Parkinson's Disease Trial, By Invitation
NCT05573542
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- A neurologist has confirmed the person's diagnosis.
- The person is male or female, aged 45 to 85 years.
- The person has provided signed informed consent to take part.
- The person meets the ROME IV criteria for irritable bowel syndrome (IBS) at the time of recruitment (confirm with trial site).
- The person has had IBS symptoms for at least 5 years.
- The person is male or female, aged 18 to 85 years.
- The person has provided signed informed consent to take part.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- The person has another confirmed gut or digestive disease, such as inflammatory bowel disease.
- The person is currently using or has recently used antibiotics within the past 12 weeks.
- The person is currently using or has recently used (within the past 4 weeks) nutritional supplements or herbal products that affect gut function or mood, such as aloe vera, St. John's Wort, probiotics, or prebiotics.
- The person has been diagnosed with a major psychiatric or physical health condition other than Parkinson's disease.
- The person has a history of alcohol or drug misuse, as assessed by a recognised screening tool or clinical judgement.
- The person has epilepsy.
- The person has had a brain bleed or has a history of brain bleeding.
- The person is pregnant or breastfeeding.
- The person has claustrophobia (fear of enclosed spaces).
- The person smokes or uses any tobacco product, including snuff.
- The person's dominant hand is their left hand.
- The person has an implanted medical device inside their body, such as a pacemaker.
- The person has aneurysm clips in their head.
- The person has a shunt in their head.
- The person has shrapnel, grenade fragments, or metal splinters anywhere in their body, including in the eyes.
- The person has metal or electrodes inside their body, such as a heart stent, cochlear implant, or temperature catheter.
- The person has extensive dental implants or dentures.
- The person has had surgery on their head.
- The person has had surgery on their heart.
- The person has swallowed a video capsule (a small camera pill used to examine the gut).
- The trial investigator has another reason to consider the person unsuitable for participation.
- The person has IBS.
- The person has another confirmed gut or digestive disease, such as inflammatory bowel disease, or has Parkinson's disease.
- The person is currently using or has recently used antibiotics within the past 12 weeks.
- The person is currently using or has recently used (within the past 4 weeks) nutritional supplements or herbal products that affect gut function or mood, such as aloe vera, St. John's Wort, probiotics, or prebiotics.
- The person has been diagnosed with a major psychiatric or physical health condition, or has a history of alcohol or drug misuse as assessed by a recognised screening tool or clinical judgement.
- The person has epilepsy, a history of brain bleeding, claustrophobia, is pregnant or breastfeeding, smokes or uses tobacco including snuff, or is left-hand dominant; or has an implanted device such as a pacemaker, aneurysm clips in the head, head shunts, metal fragments in the body, internal metal or electrodes, extensive dental implants, or has had surgery on the head or heart, or has swallowed a video capsule.
- The person has extensive dental implants or dentures, has had surgery on the head or heart, has swallowed a video capsule, or the trial investigator has another reason to consider the person unsuitable for participation.
- The following criteria apply to healthy control participants (confirm with trial site):
- The person is male or female, aged 18 to 85 years.
- The person has provided signed informed consent.
- The person is currently using or has recently used medications that affect gut bacteria, gut function, or mood — such as antidepressants (within 12 weeks) or antibiotics (within 12 weeks).
- The person has no ongoing gut or digestive symptoms.
- The person is currently using or has recently used (within the past 4 weeks) nutritional supplements or herbal products that affect gut function or mood, such as aloe vera, St. John's Wort, probiotics, or prebiotics.
- The person has been diagnosed with a major psychiatric or physical health condition.
- The person has a history of alcohol or drug misuse, as assessed by a recognised screening tool or clinical judgement.
- The person has taken proton pump inhibitors (medications that reduce stomach acid, such as omeprazole) within the past 4 weeks.
- The person has epilepsy.
- The person has had a brain bleed or has a history of brain bleeding.
- The person is pregnant or breastfeeding.
- The person has claustrophobia.
- The person smokes or uses any tobacco product, including snuff.
- The person's dominant hand is their left hand.
- The person has an implanted medical device inside their body, such as a pacemaker.
- The person has aneurysm clips in their head.
- The person has a shunt in their head.
- The person has shrapnel, grenade fragments, or metal splinters anywhere in their body, including in the eyes.
- The person has metal or electrodes inside their body, such as a heart stent, cochlear implant, or temperature catheter.
- The person has extensive dental implants or dentures.
- The person has had surgery on their head.
- The person has had surgery on their heart.
- The person has swallowed a video capsule.
- The person regularly takes anti-inflammatory medications, including NSAIDs (such as ibuprofen).
- The trial investigator has another reason to consider the person unsuitable for participation.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.
GP referral letter
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Trial details
Status
By Invitation
Phase
Not Applicable
Sponsor
Örebro University, Sweden
Registry
ClinicalTrials.gov
Start date
1 May 2023
Est. completion
1 October 2027
Where this trial is recruiting
🇸🇪 Sweden
Primary endpoints
Presence of alpha-synuclein
Can't join this trial?
Data last synced from ClinicalTrials.gov: 31 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.
Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.