Huntington's Disease Trial, Recruiting NCT06082713 Sponsor: University of Central Florida Condition: Huntington's Disease
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Huntington's Disease Trial, Recruiting

NCT06082713
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 18 and 75 years old
  • You are able to give your informed consent to take part
  • You are able to read and speak English
  • You are willing to follow the study procedures, which include fasting overnight, having blood taken, and having a lumbar puncture (a procedure where a small amount of fluid is taken from your lower back)
  • You have either been diagnosed with Huntington's disease (HD) or have not been diagnosed with HD

Who may not be able to join:

  • You are younger than 18 or older than 75 years old
  • You carry a specific intermediate or very large number of CAG gene repeats (a genetic variation related to HD) — confirm with trial site if unsure what this means for you
  • You receive your nutrition through a feeding tube
  • You are pregnant
  • You have taken part in a clinical drug trial in the last 30 days
  • You take prescribed or non-prescribed medications that may affect blood clotting or cause excessive bleeding
  • You have tested positive for HIV, hepatitis B, or hepatitis C
  • You have a confirmed or suspected condition that weakens your immune system
  • You have a significant medical, psychiatric, or neurological condition on the day of sample collection that may prevent you from completing the study procedures (confirm with trial site)
  • You have a fear of needles, frequent headaches, a significant problem with your lower spine, or have had major surgery
  • You have taken blood-thinning or anti-clotting medications (such as aspirin, warfarin, or similar drugs) within the 14 days before sample collection
  • You have a disorder that affects blood clotting or causes unusual bruising
  • You are unwilling or unable to follow any of the study procedures

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Amber Southwell, PhD, University of Central Florida Burnett School of Biomedical Sciences

Phone: 4072668742

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University of Central Florida
Registry
ClinicalTrials.gov
Start date
25 October 2023
Est. completion
1 November 2031

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

To discover blood-based biomarker of brain HTT protein using extracellular vesicles to be used in evaluating target engagement in HTT lowering clinical trials.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov