Parkinson's Disease Trial, Not Yet Recruiting NCT06762028 Sponsor: University of Calgary Condition: Parkinson's Disease
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Parkinson's Disease Trial, Not Yet Recruiting

NCT06762028
Not Yet Recruiting Not Applicable

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • Men and women between 50 and 85 years old at the time of the on-site visit (those aged 81–85 will be considered individually by the lead researcher).
  • People who have given their signed agreement to take part in the study.
  • People who are willing and able to follow the study procedures, including swallowing a special study capsule, and attending required assessments.
  • People who are able to swallow a size-00 capsule (25mm long) while in the "off" state (when Parkinson's symptoms are less controlled).
  • People who have been diagnosed with idiopathic Parkinson's disease (clinically probable), including confirmed responsiveness to levodopa medication.
  • People who are currently taking an immediate-release levodopa medicine during the day at a stable dose for at least 2 months before joining the study.

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have a gut or digestive condition that may prevent a swallowed capsule from passing through and leaving the body normally.
  • People who have taken any medications in the week before the on-site visit that could significantly affect how the digestive system moves, unless those medications are part of their regular ongoing treatment.
  • People with a history of difficulty swallowing (affecting the mouth or throat), or any other swallowing disorder that could risk the capsule being inhaled into the airway (for example, a score above 4 on a swallowing difficulty questionnaire).
  • People who have received, or are currently receiving, strong anti-inflammatory or immune-suppressing medicines within 2 months of the on-site visit — such as DMARDs, biologics, or oral steroids — except for occasional use of certain anti-inflammatory medicines (NSAIDs) or a specific bowel treatment called mesalazine (5-ASA).
  • People who have had an active cancer diagnosis within the past 5 years.
  • People who have a clinically significant problem with their immune system, as determined by the investigator.
  • People who have used antibiotics (other than those applied directly to the skin or a local area) within 12 weeks before the on-site visit, or who have ever had a faecal microbiota transplant (a procedure involving transfer of gut bacteria).
  • People who have used prebiotic or probiotic supplements within 2 weeks before the on-site visit.
  • People who have a history of dementia.
  • People who have insulin-dependent diabetes.
  • People currently experiencing a psychosis episode, as assessed by the clinical team.
  • People who are pregnant.
  • People with current alcohol or drug abuse.
  • People who are currently receiving deep brain stimulation treatment or using Duodopa/Lecigon (a gel-based levodopa delivery system).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 4032108726

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Not Applicable
Sponsor
University of Calgary
Registry
ClinicalTrials.gov
Start date
1 February 2025
Est. completion
1 February 2027

Primary endpoints

Change of Part 3 score of the MDS-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) on L-dopa challenge test

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov