Phase 3 Ovarian Cancer Trial, Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- You must be willing to sign consent forms before any trial-related procedures begin, including consent for optional genetic testing.
- You must be 18 years of age or older at the time of signing the consent form.
- You have been diagnosed with a specific type of ovarian, fallopian tube, or primary peritoneal cancer (a high-grade epithelial type, confirmed by tissue testing), including types such as serous, endometrioid, clear cell, carcinosarcoma, or mucinous.
- You have been newly diagnosed with an advanced stage of the disease (Stage III or IV).
- Your cancer must show a certain level of a protein called HER2, confirmed through a specific type of tissue test sent to a central laboratory.
- You must have enough tumor tissue available (a tissue block or slides) for laboratory testing, including HER2 testing and other analysis.
- You must have an available local test result for HRD (a measure of DNA repair in cancer cells) or BRCA gene status.
- You have already received up to 6 cycles of standard chemotherapy (platinum-based) combined with a drug called bevacizumab, and your doctor considers you suitable to continue with bevacizumab alone as a maintenance treatment.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- Your ovarian, fallopian tube, or peritoneal cancer is not of the epithelial type (confirm with trial site).
- You have a known harmful change in the BRCA gene that would make you eligible for a type of drug called a PARP inhibitor.
- Your doctor has determined that you should receive a PARP inhibitor as part of your standard maintenance treatment.
- You have had a serious allergic reaction to any of the drugs used in this trial or to similar types of medications (monoclonal antibodies).
- You have had a stroke, mini-stroke (TIA), or a type of brain bleed (subarachnoid hemorrhage) within the 6 months before joining the trial.
- You have a condition where your blood does not clot properly (and you are not on blood-thinning medication).
- You have a history of abnormal bleeding, an abnormal opening in the bowel or abdomen (fistula or perforation), or active bleeding in the digestive system within the past 6 months.
- You currently have a blockage in your bowel.
- You have had a heart attack within the past 6 months, or you have moderate-to-severe heart failure symptoms.
- Your heart's electrical activity (measured by an ECG test) shows a specific abnormality called a prolonged QT interval above a certain level.
- You have a history of a lung condition called interstitial lung disease (ILD) or pneumonitis that needed steroid treatment, or you currently have this condition, or it cannot be ruled out based on your scans.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 908-992-6400
Australian sites
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
6 site(s) in Australia. Confirm current status and contact details directly with the trial site.
Primary endpoints
Progression Free Survival by Blinded Independent Central Review (BICR) in the HER2 IHC 3+/2+ population
Can't join this trial?
Data last synced from ClinicalTrials.gov: 24 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.