Printed from Voxsanity (voxsanity.com.au) — NCT06825455 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.
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Early Phase 1 Ovarian Cancer Trial, Not Yet Recruiting
NCT06825455
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- People aged 18 or older (any gender).
- People whose doctors expect them to survive at least 3 months.
- People with a good general level of physical functioning, able to carry out normal daily activities with little or no restriction (confirm with trial site — this refers to an ECOG score of 0–1).
- People who have a confirmed diagnosis of a solid malignant (cancerous) tumour that has stopped responding to standard treatments.
- People whose tumour tissue has tested positive for a protein called B7H3, detected through a laboratory test on a tissue sample (a sample taken within the last year is preferred).
- People who have at least one tumour area that can be measured and tracked during the trial.
- For people in the surgical (laparotomy) group specifically: tumours must be limited to the lining of the abdomen (peritoneal metastases) or the ovaries.
- People whose blood, liver, kidney, heart, and lung function results meet the required levels before the first treatment (specific laboratory values apply — confirm with trial site).
- Women who could become pregnant must have a negative pregnancy test before joining, and both men and women must agree to use effective contraception during treatment and for one year afterwards.
- People who are able to understand what the trial involves and are willing to follow its requirements.
- People who are willing to sign the trial's informed consent form.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People with a known allergy, sensitivity, or intolerance to cell infusions or to any of the medications that may be used in the trial, including fludarabine and cyclophosphamide.
- People who have been continuously taking immune-suppressing medications within one month before the cell infusion.
- People who have had a stroke or seizure within six months before signing the consent form.
- People who have brain metastases (cancer that has spread to the brain) that are causing symptoms.
- People with a known psychiatric condition or substance use disorder that would make it difficult to follow the trial requirements.
- People who test positive for hepatitis B, hepatitis C (with active virus detected in the blood), HIV, or syphilis (specific test combinations apply — confirm with trial site).
- People with serious heart conditions, including unstable chest pain (angina), a heart attack within the past six months, significant heart failure, or severe irregular heartbeat.
- People with an active or uncontrolled infection that requires systemic (whole-body) treatment, except for mild urinary tract or upper respiratory infections.
- People who have not yet recovered from significant side effects caused by a previous treatment (side effects at Grade 2 or higher, except where related to the cancer itself or a pre-existing condition).
- People who have a confirmed diagnosis of an immune deficiency condition.
- People with an active infection currently requiring systemic treatment.
- Women who are capable of becoming pregnant and plan to do so within two years of the cell infusion, or men whose partner plans to become pregnant within two years of the cell infusion.
- People who have taken part in a clinical trial of another experimental drug within one month before screening.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.
Contact this trial
Phone: 010-88196561
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Status
Not Yet Recruiting
Phase
Early Phase 1
Sponsor
Peking University
Registry
ClinicalTrials.gov
Start date
1 March 2025
Est. completion
31 December 2027
Where this trial is recruiting
🇨🇳 China
Primary endpoints
Incidence of Adverse Events (AEs)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 29 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.
Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.