Huntington's Disease Trial, Recruiting NCT06843252 Sponsor: The University of Texas Health Science Center at San Antonio Condition: Huntington's Disease
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Huntington's Disease Trial, Recruiting

NCT06843252
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are between 18 and 85 years old and have been confirmed to carry the Huntington's disease (HD) gene mutation and/or have a family history of HD along with typical symptoms such as involuntary movements (chorea).
  • Your HD is in an early or moderate stage (stages 1, 2, or 3) based on a standard rating scale used for Huntington's disease.
  • You have mild to moderate behavioral symptoms related to HD, but none that are considered severe (based on a specific symptom rating scale — confirm with trial site).
  • You have been on stable doses of any medications for at least one month before joining.
  • You are willing and able to read, understand, and sign a consent form agreeing to take part.
  • You have a caregiver (an unpaid family member or friend) who is willing to be present during treatment sessions and fill out questionnaires.

For caregivers, they must also:

  • Be an adult who provides unpaid care to someone enrolled in the study.
  • Have the mental capacity to give verbal consent to take part in the caregiver portion of the study.
  • Be able to read, write, hear, and communicate well enough to answer questions about the person they care for.

Who may not be able to join:

  • You have unstable or poorly controlled medical conditions, such as unstable chest pain, uncontrolled diabetes, uncontrolled high blood pressure, or advanced cancer.
  • You have a history of epilepsy (seizures).
  • You have been diagnosed with a major memory or thinking disorder, such as dementia.
  • You have had thoughts of suicide with some intention to act on them, or a specific plan to do so, in the three months before screening.
  • You are currently taking part in another clinical treatment trial.
  • It has been determined that you are not able to give informed consent to participate.
  • You have a pacemaker or any other implanted medical device that would make the brain stimulation treatment used in this trial (called tDCS) unsafe for you.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Thiago Macedo e Cordeiro, MD, MSc, The University of Texas Health Science Center at San Antonio

Phone: 210-450-7055

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
The University of Texas Health Science Center at San Antonio
Registry
ClinicalTrials.gov
Start date
2 September 2025
Est. completion
1 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Percentage of Participants that met Inclusion Criteria; Percentage of Participants that Agreed to Randomization; Completed period 1 of study; Completed period 2 of study; Completion of study to last visit; TDCS Acceptability Scale; tDCS Side Effects Scale

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov