Printed from Voxsanity (voxsanity.com.au) — NCT06846424 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.
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Phase 1 Ovarian Cancer Trial, Not Yet Recruiting
NCT06846424
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- People aged 18 or older.
- People whose general health and ability to carry out daily activities meets a certain minimum level (measured by standard performance scales used by doctors).
- People with epithelial ovarian, fallopian tube, or peritoneal cancer that has come back or stopped responding to treatment, confirmed by lab testing of tissue or cell samples, and for whom standard treatments have failed, are no longer tolerated, or are no longer available.
- People from whom a tumor tissue or cell sample can be obtained, for example through a biopsy.
- People whose tumor cells have tested positive for a protein called TAG-72, confirmed by a specific lab staining test (IHC).
- People whose doctors estimate they are likely to live for more than 3 months.
- People who have at least one measurable tumor that can be tracked according to standard criteria (RECIST 1.1).
- People whose blood counts meet required minimums before starting treatment: enough neutrophils (a type of white blood cell), lymphocytes (another immune cell), haemoglobin (a measure of red blood cells), and platelets.
- People whose kidneys are functioning well enough, based on a blood test result within an acceptable range.
- People whose liver is functioning well enough, based on blood test results within acceptable ranges.
- People whose blood clotting measures are within acceptable ranges.
- People who are not pregnant (confirmed by a negative blood pregnancy test within 7 days before joining), are not breastfeeding, and who agree to use adequate contraception during the trial and for 6 months after it ends.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who have a known allergy to any ingredient in the study treatment (SCT-001 CAR-T cell injection).
- People who have received anti-cancer treatments — such as chemotherapy, radiation, biological therapy, hormone therapy, targeted therapy, or immunotherapy — or who have taken part in another clinical trial within 4 weeks before the first dose, or within 5 half-lives of the previous treatment drug (whichever is the shorter period).
- People who have received certain traditional Chinese medicine or modern Chinese medicine products with listed anti-tumour uses within 14 days before the first dose.
- People who still have side effects from previous cancer treatment that have not resolved to a mild or absent level (with some exceptions, such as hair loss, at the doctor's judgement).
- People who have had surgery within 4 weeks before treatment, or who have not fully recovered from a previous invasive procedure.
- People who have cancer that has spread to the brain or the membranes surrounding the brain or spinal cord, if those areas are not well controlled or are causing symptoms, as judged by the doctor.
- People who have an active infection of a certain severity, or who are assessed by the doctor as having a suspected risk of infection.
- People with a history of autoimmune disease, immune deficiency, a positive HIV test, other acquired or inherited immune deficiency conditions, or a history of organ transplantation.
- People with active hepatitis B or active hepatitis C.
- People who have previously received any immune cell therapy.
- People with a history of serious heart conditions, such as certain abnormal heart rhythms or electrical conduction problems, heart attack, coronary artery bypass surgery, heart failure of a certain severity, reduced heart pumping function, blood clots, or abnormal heart rhythm measurements (QTcF) above set limits.
- People with a history of serious brain or blood vessel conditions such as stroke.
- People who would need to receive other anti-cancer treatments at the same time as the study treatment (including radiation, chemotherapy, immunotherapy, targeted therapy, or traditional Chinese medicine therapy).
- People with a previously diagnosed neurological or psychiatric condition, including epilepsy or dementia.
- People who, in the doctor's judgement, have any other reason that makes participation in this trial unsuitable.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
GP referral letter
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Trial details
Status
Not Yet Recruiting
Phase
Phase 1
Sponsor
Shanghai Gynecologic Oncology Group
Registry
ClinicalTrials.gov
Start date
1 June 2025
Est. completion
1 June 2027
Where this trial is recruiting
🇨🇳 China
Primary endpoints
Incidence of dose limiting toxicities (DLTs); Incidence of adverse events
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.
Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.