Printed from Voxsanity (voxsanity.com.au) — NCT06884059 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.
Back to Type 2 Diabetes
Phase 1 Type 2 Diabetes Trial, Recruiting
NCT06884059
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- People aged between 18 and 75 years old.
- People who have Type 2 diabetes with a blood sugar control reading (A1c) between 6.5% and 9.0%, who are on stable diabetes medications, and who are able to walk and move around on their own.
- People who have a urine test result showing a moderate level of protein leakage into the urine (urine albumin creatinine ratio between 30 and 300 mg).
- People who are willing to use a smartphone (Apple or Android) for study activities.
- People who currently eat across a window of 12 or more hours per day and have logged enough data in the study's app before starting.
- People who are capable of becoming pregnant will be given a pregnancy test at the start of the study and will be asked to use contraception throughout.
- People who have gone through menopause, or who are on hormone replacement therapy, are eligible to participate.
- People whose kidney filtering rate (eGFR) is above 45.
- People who are taking heart or cholesterol medications (such as statins, other cholesterol-lowering drugs, or blood pressure medications) may participate, but those medication doses must remain unchanged during the study.
- People who have been on a stable dose of GLP-1 receptor agonist medications (a type of diabetes or weight-related medication) for at least 3 months are eligible to participate.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People with Type 1 diabetes, or people with Type 2 diabetes who are taking insulin or sulfonylurea medications, or who have an HbA1c above 9%.
- People whose kidney filtering rate (eGFR) is below 45.
- People with a systolic (top number) blood pressure above 160 mmHg and/or a diastolic (bottom number) blood pressure above 110 mmHg, whether or not they are on blood pressure medication.
- People with LDL ("bad") cholesterol above 200 mg/dL.
- People with triglyceride (a type of blood fat) levels above 500 mg/dL.
- People who currently smoke tobacco or use illicit drugs.
- People who are pregnant or breastfeeding.
- People who are currently enrolled in a weight-loss or weight-management program.
- People who are currently following a special or medically prescribed diet for another condition (for example, a gluten-free diet for coeliac disease).
- People who have recently been prescribed a medication intended for weight loss or known to reduce appetite (though people who have been on a stable dose of such a medication for 3 months may be eligible — confirm with trial site).
- People with a history of an eating disorder.
- People who have had surgery for weight management, or who have an active eating disorder.
- People with chronic kidney disease where kidney filtering function (eGFR calculated using the MDRD method) is below 50 mL/min/1.73m² (confirm with trial site).
- People currently receiving treatment for an active inflammatory condition, rheumatologic (joint or autoimmune) disease, or cancer.
- People who have had a major heart or cardiovascular event in the past 6 months, such as a heart attack, a procedure to open blocked heart arteries, heart bypass surgery, hospitalisation for heart failure, or a stroke or mini-stroke.
- People with a history of uncontrolled irregular heart rhythm (note: rate-controlled atrial fibrillation or atrial flutter are not exclusions — confirm with trial site).
- People with liver cirrhosis or significant problems with liver function.
- People with a history of thyroid disease whose thyroid medication dose has needed adjusting in the past 3 months (note: people with hypothyroidism on a stable thyroid medication dose are not excluded — confirm with trial site).
- People who work shift work with changing or night-time hours.
- People who regularly care for dependents and experience frequent overnight disruptions to their sleep.
- People who have more than one trip planned during the study period to a destination in a time zone more than 3 hours different from their own.
- People with a history of a major heart or cardiovascular event within the past year, including heart attack, heart artery procedures, bypass surgery, hospitalisation for heart failure, or stroke or mini-stroke.
- People with a history of thyroid disease that has required a change in thyroid medication dose within the past 3 months (stable hypothyroidism on unchanged medication is not an exclusion — confirm with trial site).
- People with a history of adrenal gland disease.
- People with a history of cancer who are currently undergoing active treatment, except for certain non-melanoma skin cancers.
- People with a known history of Type 1 diabetes.
- People with stage 4 or 5 chronic kidney disease, or who require dialysis.
- People with a known history of HIV/AIDS.
- People with an uncontrolled psychiatric condition, including a history of hospitalisation for a psychiatric illness.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Contact this trial
Principal Investigator: Pam Taub, MD, University of California, San Diego Health
Phone: (858) 246-2342
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Status
Recruiting
Phase
Phase 1
Registry
ClinicalTrials.gov
Start date
1 March 2025
Est. completion
1 February 2027
Where this trial is recruiting
🇺🇸 United States
Primary endpoints
Urine albumin-to-creatinine ratio (uACR)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.
Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.