Parkinson's Disease Trial, Recruiting NCT06928519 Sponsor: Yousheng Xiao Condition: Parkinson's Disease
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Parkinson's Disease Trial, Recruiting

NCT06928519
Recruiting Not Applicable

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • People aged between 18 and 80 years
  • People who have been diagnosed with Parkinson's Disease by a movement disorder neurologist, using recognised international diagnostic guidelines (MDS criteria)
  • People whose Parkinson's symptoms fall within a mild to moderate range, as measured by a scale called the Modified Hoehn and Yahr (stages 1 to 2.5)
  • People who have never previously used a medication called entacapone
  • People who score 26 or higher on a standard memory and thinking test called the MMSE
  • People who score below 15 on a depression questionnaire called the Beck Depression Inventory (BDI)
  • People who have either never taken levodopa before, or who have been on a steady dose of levodopa (between 300–600 mg per day) for at least one month before joining
  • People taking certain other Parkinson's medications (amantadine, anticholinergics, dopamine agonists, selegiline, or rasagiline) may still be eligible, provided the dose has been stable for at least 30 days before and throughout the study
  • People who are willing and able to agree to participate and follow study procedures, with caregiver support if needed

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have used entacapone or a similar medication called tolcapone for more than 30 days in total, or within 4 weeks before the study start date
  • People who have used dopamine agonist medications within 4 weeks before the study start date
  • People who score 15 or higher on the Beck Depression Inventory (BDI)
  • People who score below 26 on the MMSE memory and thinking test
  • People whose levodopa dose has not been stable
  • People who have a history of involuntary movements caused by Parkinson's medication (known as dyskinesia)
  • People diagnosed with an atypical or secondary form of parkinsonism, or who have had brain surgery related to Parkinson's Disease
  • People with significant health conditions in the past 5 years that could interfere with taking part in the study (confirm with trial site)
  • People taking medications known to cause Parkinson's-like symptoms as a side effect
  • People who have taken part in another clinical drug trial within 30 days before the study start date

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 31 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +86-15177196935

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Yousheng Xiao
Registry
ClinicalTrials.gov
Start date
5 June 2025
Est. completion
30 April 2027

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Change from baseline to Week 24 in the MDS-UPDRS Part III (Motor Examination) score

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 31 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov