Phase 1 Parkinson's Disease Trial, Not Yet Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- People who are able to give informed consent and follow the study procedures.
- People who are between 55 and 75 years of age at the time of signing the consent form.
- People who have been diagnosed with Parkinson's disease for more than 5 years.
- People who are currently taking levodopa and experiencing complications such as "wearing off" (the medication stopping working before the next dose) and/or dyskinesia (uncontrolled, involuntary movements).
- People who experience at least 3 hours total of "off" time (periods when medication is not working well) per day.
- People whose Parkinson's symptoms, when medication is not working, fall within Hoehn and Yahr Stage 3 to 4 — a measure of how much the disease affects movement and balance (confirm with trial site).
- People whose Parkinson's symptoms respond to dopamine medication, shown by at least a 30% improvement on a standard motor assessment scale when medication is working versus when it is not.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who have any of the following conditions: epilepsy; multiple sclerosis; dementia that prevents them from giving informed consent; an atypical form of Parkinsonism; a genetic form of Parkinson's disease; thoughts of suicide with intent or a plan in the past 12 months; a history of psychosis; a history of bleeding around the brain (subarachnoid hemorrhage); or a history of stroke or mini-stroke (transient ischemic attack).
- People who have unstable vital signs (such as blood pressure or heart rate) at the screening visit or before surgery.
- People whose kidneys are not filtering at a sufficient level, based on a standard blood test result (confirm with trial site).
- People with liver problems, shown by certain liver enzyme levels being more than three times above the normal upper limit.
- People with certain blood abnormalities, including low haemoglobin or a low platelet count (confirm with trial site for specific thresholds).
- People with a blood clotting measure (INR) of 1.3 or higher, where this is not caused by something that can be reversed.
- People who have an autoimmune disorder.
- People who have HIV, or active hepatitis B or hepatitis C infection.
- People who are unable to undergo MRI or PET/CT scans.
- People whose life expectancy is less than one year.
- People who have or have had an active cancer.
- People who are currently receiving levodopa-carbidopa intestinal gel or apomorphine as a treatment.
- People who have previously had pallidotomy, thalamotomy, or deep brain stimulation (DBS) surgery.
- People who have received cell or gene therapy within the previous 12 months.
- People who have taken part in another clinical trial of an investigational treatment or device within the past 30 days.
- People who are pregnant or breastfeeding.
- People who have other conditions that the research team considers unsuitable for participation in this study.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
If you need support right now
This page includes language about suicide and self-harm, because that is how the trial's eligibility criteria are written. If reading it has been hard, you do not have to keep going. The services below are free, confidential, and answered by people trained for exactly this.
If you or someone else is in immediate danger, call 000.
- Lifeline — 24/7 crisis support: 13 11 14
- Suicide Call Back Service — 24/7 counselling: 1300 659 467
- 13YARN — 24/7, for Aboriginal and Torres Strait Islander people: 13 92 76
- Beyond Blue — 24/7 mental health support: 1300 22 4636
- Emergency: 000
Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention. If you are in immediate danger, call your local emergency number.
Voxsanity is not a crisis service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.
If this is close to home
This page includes language about advanced illness, prognosis, or palliative care, because that is how the trial's eligibility criteria are written. Seeing it set out plainly can land hard, whether it is about you or about someone you are caring for. You do not have to be at a crisis point to talk to someone.
- Griefline — grief and loss counselling, 9am to 6pm weekdays and midday to 6pm weekends (AEST/AEDT): 1300 845 745
- Carer Gateway — practical and emotional support if you are caring for someone, 8am to 5pm weekdays: 1800 422 737
- Canteen — for 12 to 25 year olds affected by cancer, their own or a family member's: 1800 945 215
- Palliative Care Australia — directory of palliative care services near you: palliativecare.org.au
- Lifeline — 24/7, for any kind of distress, at any hour the services above are closed: 13 11 14
Palliative care is not the same as giving up on treatment, and it is not only for the last weeks of life. It is symptom and comfort care that can run alongside active treatment, including a clinical trial.
Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of support and crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention.
Voxsanity is not a counselling or medical service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.
Contact this trial
Principal Investigator: Gao Chen, PhD, MD, Second Affiliated Hospital, School of Medicine, Zhejiang University
Phone: +86 13868137422
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Incidence and servility of Treatment-Emergent Adverse Events
Can't join this trial?
Data last synced from ClinicalTrials.gov: 10 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.