Printed from Voxsanity (voxsanity.com.au) — NCT07273396 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.
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Phase 2 Ovarian Cancer Trial, Not Yet Recruiting
NCT07273396
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- Women between the ages of 19 and 85 years old.
- People who have been diagnosed with ovarian, fallopian tube, or peritoneal cancer, confirmed through laboratory testing of tissue samples.
- People whose cancer either progressed during platinum-based chemotherapy (refractory), or came back within 6 months of finishing platinum-based chemotherapy (resistant).
- People who have received at least 2 previous intravenous (IV) chemotherapy treatments (which may include a drug called paclitaxel).
- People whose cancer has not responded to standard treatments, or for whom standard treatments are not suitable due to intolerances or allergic reactions, and who are also not suitable for surgery to remove the cancer.
- People who have at least one measurable or detectable area of cancer in the peritoneum (the lining of the abdomen), as assessed using standard imaging guidelines.
- People who have no more than one area of cancer that has spread to distant parts of the body, and that area is causing no symptoms (not counting spread to certain lymph nodes, fluid around the lungs, or limited skin involvement).
- People whose peritoneal cancer spread has been confirmed by PET-CT or CT scan imaging.
- People with a general physical functioning level rated 0, 1, or 2 on the ECOG scale, which broadly means people who are fully active, have some limitations, or are able to care for themselves but cannot work (confirm with trial site).
- People who are not currently pregnant or breastfeeding, and — for those who could become pregnant — people willing to use a highly effective form of contraception (such as an intrauterine device or surgical sterilisation) for 6 months after the last treatment.
- People whose blood, liver, and kidney results fall within the required ranges, specifically: sufficient white blood cell counts, platelets, and haemoglobin levels; liver enzyme and bilirubin levels within acceptable limits; kidney function within acceptable limits; and normal blood clotting results (confirm specific values with trial site).
- People whose lung function test results are at or above 70% of the expected level for their age and size.
- People who have read, understood, and signed a consent form agreeing to take part in the trial.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who have 2 or more areas where cancer has spread to distant parts of the body (not counting certain lymph nodes, fluid around the lungs, or limited skin involvement).
- People for whom the drug paclitaxel is medically not recommended, based on official prescribing guidelines.
- People who have a history of serious allergic reactions to paclitaxel or to the medical devices used in the PIPAC procedure.
- People with certain serious or uncontrolled health conditions, including: moderate or severe heart failure; significant heart or cardiovascular disease such as irregular heartbeat or a recent heart attack; conditions or treatments that weaken the immune system (such as AIDS, certain autoimmune diseases, or immunosuppressive medications); active hepatitis B or hepatitis C infection; high blood pressure that is not well controlled; or diabetes that is not well controlled.
- People who have a bowel obstruction (a blockage in the bowel) confirmed by imaging or clinical assessment.
- People who have received IV chemotherapy within the 4 weeks before starting the first cycle of the trial treatment.
- People whose life expectancy is estimated to be less than 3 months.
- People who have previously received PIPAC therapy.
- People who are not medically suitable for general anaesthesia or keyhole (laparoscopic) surgery.
- People who are unwilling to use a medically acceptable form of contraception, defined as methods with a very low failure rate such as an intrauterine device or surgical sterilisation (tubal ligation, hysterectomy, or vasectomy).
- People who have taken part in another clinical trial within 1 month before the screening visit for this trial.
- People whom the trial investigators determine are not suitable for other reasons based on their medical judgement.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Contact this trial
Principal Investigator: Hee Seung Kim, MD, PhD, Seoul National University College of Medicine
Phone: 82-02-2072-4863
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Status
Not Yet Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
1 January 2026
Est. completion
30 April 2030
Primary endpoints
Dose limiting toxicities; Maximum tolerated dose; Recommended Phase 2 Dose; Disease control rate
Can't join this trial?
Data last synced from ClinicalTrials.gov: 24 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.
Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.