Type 2 Diabetes Trial, By Invitation
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- Adults between 18 and 50 years of age.
- People who are classified as generally healthy with no serious medical conditions (known as ASA Class I status — confirm with trial site if unsure what this means).
- People who have been diagnosed with Type 2 diabetes, with a blood sugar control measure (called HbA1c) between 5.5% and 9.0%, confirmed by medical records and lab tests.
- People who have a specific type of tooth infection (called chronic apical periodontitis) affecting their upper or lower front teeth or lower premolars.
- Teeth that have had a previous root canal treatment that needs to be redone, and which show a certain level of infection on dental X-ray (a PAI score of 3 or higher — confirm with trial site for details).
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who have any significant health condition beyond well-controlled health (classified as ASA Class II or higher — confirm with trial site).
- People who are pregnant or may be pregnant.
- People who have gum disease affecting one or more teeth (localised or generalised periodontitis).
- People who have certain inflammatory or immune system conditions, including hepatitis, HIV infection, conditions treated with chemotherapy that affects the immune system, bleeding disorders, Behçet's syndrome, or arthritis.
- People whose HbA1c blood sugar measure is above 9%.
- People who have taken antibiotics in the past month, or anti-inflammatory medicines (such as pain or swelling relief drugs) in the past week.
- People who smoke.
- People who have gum pockets deeper than 3 mm around the tooth being treated.
- People who have root resorption (breakdown of the tooth root, either from inside or outside the root).
- People who have swelling, tenderness when pressing on the area, or a dental abscess opening (fistula) near the tooth being treated.
- People who have a cracked tooth root or an incompletely formed tooth root.
- Teeth that cannot be properly isolated using a rubber dam (a dental protective sheet used during treatment) will not be included.
- Patient information including name, age, gender, contact details, and the tooth being treated will be recorded, and dental X-rays will be taken before treatment to assess the tooth (confirm with trial site regarding data and privacy procedures).
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
This date has passed while the registry still lists the trial as open to participants. Sponsors often update a trial's status without revising its projected end date, so it may well still be recruiting — but the record is out of date in at least one respect. Check with the study contact before relying on either.
Where this trial is recruiting
Primary endpoints
TLR9 expression levels in periapical exudate and gingival crevicular fluid samples
Can't join this trial?
Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.