Phase 3 Type 2 Diabetes Trial, Recruiting NCT07428746 Sponsor: Emory University Condition: Type 2 Diabetes
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Phase 3 Type 2 Diabetes Trial, Recruiting

NCT07428746
Recruiting Phase 3

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • Women who have gone through menopause and are aged 65 years or older
  • People who have been diagnosed with type 2 diabetes
  • People with a Body Mass Index (BMI) between 27 and 40 (inclusive)
  • People whose blood sugar control measure (HbA1c) was between 7% and 10% within the 3 months before their first visit
  • People who are willing and able to follow all study procedures, including fasting requirements at certain visits
  • People who have had a bone density scan (DEXA scan) within the last 12 months confirming they do not have osteoporosis
  • People who are able to give informed consent and take part in all study assessments

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People who have type 1 diabetes, or any form of diabetes other than type 2
  • People whose kidney function test (eGFR) result was below 30 ml/min in the last 3 months
  • People who have previously been treated with medications used to prevent or treat osteoporosis
  • People whose bone density scan (DEXA scan) within the last 12 months showed primary or secondary osteoporosis, or who are currently taking osteoporosis medications
  • People who have an artificial joint, implant, or medical device in their spine or hip
  • People who have previously had a fragility fracture (a bone break caused by a minor injury due to weaker bones)
  • Men
  • People with moderate to severe gastroesophageal reflux disease (persistent, significant heartburn or acid reflux) based on their medical history
  • People who are unable to follow the treatment protocol or understand the consent form
  • People whose liver enzyme levels (AST or ALT) are more than 3 times the normal range
  • People with an uncontrolled thyroid or parathyroid condition that could affect the study results
  • People with a personal or family history of a specific type of thyroid cancer called medullary thyroid carcinoma
  • People with a personal or family history of a condition called multiple endocrine neoplasia type 2 syndrome
  • People with a personal history of any of the following conditions: delayed stomach emptying (gastroparesis), celiac disease, low sex hormone levels (hypogonadism), severe chronic obstructive pulmonary disease (COPD), underactive pituitary gland (hypopituitarism), or Cushing's disease
  • People with a personal history of severe diabetic eye disease (severe diabetic retinopathy)
  • People who have had a serious allergic reaction, including anaphylaxis or severe swelling (angioedema), to semaglutide or any of its ingredients
  • People who have used any of the following medications in the 6 months before screening: GLP-1 receptor agonists, GIP analogues, pioglitazone, or DPP-4 inhibitors
  • People who are currently being treated with a GLP-1 receptor agonist medication
  • People who have used high-dose corticosteroids (taken by mouth, injection into a vein, or injection into a joint) for more than 7 days in a row within the 2 months before screening
  • People who have used weight-loss medications or had weight-loss surgery in the 6 months before screening, or who are currently following an active weight-loss plan rather than a weight maintenance plan
  • People who are currently incarcerated

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 31 July 2026

Contact this trial

Principal Investigator: Thaer Idrees, MD, FSSCI, Emory University

Phone: 404-251-5357

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Registry
ClinicalTrials.gov
Start date
1 April 2026
Est. completion
1 November 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in handgrip strength

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 31 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov