Early Phase 1 Type 2 Diabetes Trial, Not Yet Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- Adults aged 18 to 65 years old
- People living with obesity and insulin resistance (a condition where the body doesn't respond well to insulin)
- People with a Body Mass Index (BMI) between 30 and 45 kg/m²
- Men with a waist measurement of 102 cm or more, or women with a waist measurement of 88 cm or more
- People with a HOMA-IR score of 2.5 or higher (a measure of insulin resistance calculated from a blood test — confirm with trial site)
- Healthy adults with a normal body weight
- People with a BMI between 18 and 25 kg/m²
- Men with a waist measurement under 94 cm, and women with a waist measurement under 80 cm
- People with a HOMA-IR score below 2
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who are pregnant or breastfeeding
- People who are unable to give informed consent to participate
- People who have diabetes or polycystic ovarian syndrome (PCOS)
- People with a known history of heart or blood vessel disease, including heart failure, coronary artery disease, peripheral artery disease, or stroke
- People with a nerve or neurological condition
- People with poorly controlled high blood pressure (systolic above 180 mmHg and/or diastolic above 100 mmHg)
- People with an active cancer diagnosis, except for certain minor skin cancers (basal cell carcinoma or early-stage squamous cell carcinoma of the skin)
- People who currently smoke or use tobacco or nicotine products
- People currently taking prescription medication for weight loss
- People whose body weight has changed by more than 10% in the past 6 months
- People who already do more than 150 minutes per week of moderate to vigorous physical activity or exercise
- People who have taken part in another research study or medical procedure involving significant radiation exposure in the past 12 months
- People who experience claustrophobia (fear of enclosed spaces)
- People who have metal implants in their body that are not safe for use in an MRI machine
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 573-882-2544
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Amount of muscle sympathetic nerve activity (MSNA); Amount of cerebral blood flow; Amount of leg blood flow
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.