Parkinson's Disease Trial, Not Yet Recruiting
voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice
Who may and may not be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who may be able to join
- People aged 21 to 80 years old.
- People who have been clinically diagnosed with Parkinson's disease, as defined by the Movement Disorder Society criteria.
- People who have adequate vision, hearing, thinking ability, and physical capability to participate.
Who may not be able to join
Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.
- People who have been diagnosed with a secondary or atypical form of parkinsonism (a condition that resembles Parkinson's disease but has a different cause).
- People whose blood test results fall outside acceptable ranges, including: low red blood cell levels (Hgb below 10); low platelet count (below 70,000); elevated liver enzymes (ALT or AST more than 2.5 times the upper limit of normal); reduced kidney function or moderate-to-severe liver impairment based on specific blood markers; or abnormal blood clotting results (confirm with trial site for exact values).
- People with significant memory or thinking problems, based on a score below a certain threshold on a standard cognitive test called the MoCA (confirm with trial site for exact cut-off score).
- People whose weight is above 400 lbs or whose body mass index is above 35 kg/m² (confirm with trial site).
- People whose symptoms or test results suggest another brain or nerve condition besides Parkinson's disease, such as Huntington's disease, Alzheimer's disease, dementia with Lewy Bodies, or certain infections or nutritional deficiencies affecting the brain, among others.
- People who have had active thoughts of suicide in the 6 months before screening, who answer yes to certain questions on a standard suicide assessment scale, who have attempted suicide in the past 2 years, or who the trial investigator considers to be at serious risk of suicide.
- People who currently have cancer or who have had a cancerous tumour in the past 5 years (note: people with stable untreated prostate cancer, or treated skin cancers such as squamous or basal cell carcinoma, are not excluded).
- People with any other medical condition that, in the investigator's opinion, could put them at risk, affect the study results, or prevent full participation.
- People who weigh more than 400 lbs, which is the weight limit for the MRI table used in the study.
- People who are currently pregnant, breastfeeding, or lactating.
- People who have had alcohol or substance abuse or dependence problems within the past 2 years.
- People who have had a confirmed COVID-19 infection within 6 weeks before the screening visit.
- People who still have unresolved COVID-19 symptoms, or ongoing thinking or other problems linked to long COVID, that could affect their safety or the study's cognitive assessments, based on the investigator's judgement.
- People who are currently taking part in another clinical trial involving an investigational (unapproved) treatment and have taken at least one dose within 4 weeks before screening, or within five half-lives of that drug — whichever is longer — unless they have been confirmed to be on placebo.
- People who have had gastrointestinal (digestive tract) surgery, except for appendix removal, haemorrhoid surgery, or gallbladder removal, which do not exclude participation.
- People who have used antibiotics or other medications known to affect gut bacteria within the 4 weeks before enrolling in the trial.
- People who regularly use medications that can affect the intestinal lining, such as anti-inflammatory pain relievers (NSAIDs) taken more than 3 times per week.
- People who have any condition that prevents them from safely having an MRI scan (confirm with trial site for the full list of MRI exclusions).
- People who are allergic to pineapple.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
If you need support right now
This page includes language about suicide and self-harm, because that is how the trial's eligibility criteria are written. If reading it has been hard, you do not have to keep going. The services below are free, confidential, and answered by people trained for exactly this.
If you or someone else is in immediate danger, call 000.
- Lifeline — 24/7 crisis support: 13 11 14
- Suicide Call Back Service — 24/7 counselling: 1300 659 467
- 13YARN — 24/7, for Aboriginal and Torres Strait Islander people: 13 92 76
- Beyond Blue — 24/7 mental health support: 1300 22 4636
- Emergency: 000
Outside Australia? The numbers above are Australian and will not work from overseas. Find a Helpline is a free directory of crisis lines in over 130 countries, run by ThroughLine with the International Association for Suicide Prevention. If you are in immediate danger, call your local emergency number.
Voxsanity is not a crisis service, and nothing on this page is medical advice. More Australian services are listed on our support lines page.
Contact this trial
Phone: 617-724-6086
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Primary endpoints
Gastric outcomes (accommodation and emptying) during UROstim administration as measured by gastric MRI; Brain activity during UROstim administration as measured by fMRI
Can't join this trial?
Data last synced from ClinicalTrials.gov: 31 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.