Type 2 Diabetes Trial, Not Yet Recruiting NCT07697612 Sponsor: Singapore General Hospital Condition: Type 2 Diabetes
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Type 2 Diabetes Trial, Not Yet Recruiting

NCT07697612
Not Yet Recruiting Not Applicable

voxsanity.com.au · Eligibility summary from public government registries · 18 August 2026 · not medical advice

Who may and may not be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who may be able to join

  • Adults aged between 21 and 70 years.
  • People who have been diagnosed with type 2 diabetes.
  • People who agree to eat durian for 2 weeks as part of the study.
  • People with a body mass index (a measure of body weight relative to height) between 25 and 40 kg/m².

Who may not be able to join

Each point below is a reason the trial team may not be able to accept someone. It is not a list of requirements to meet.

  • People with a known or suspected intolerance or allergy to durian.
  • People who have had a skin reaction to the adhesive used in a continuous glucose monitoring sensor (a small device worn on the skin to track blood sugar).
  • People whose diabetes is not well controlled, measured by a blood test result called HbA1c being above 8.5%.
  • People with severely elevated triglycerides (a type of fat found in the blood) above 4.5 mmol/L.
  • People who currently smoke.
  • People who have previously had surgery on the digestive system, including removal of the gallbladder, stomach, part of the bowel, or weight-loss surgery.
  • People who have inflammatory bowel disease (a condition causing long-term inflammation of the digestive tract).
  • People whose kidneys are not filtering blood well enough, based on a specific kidney function measurement falling below 30 mL/min.
  • People with elevated liver enzyme levels (ALT) more than three times the normal upper limit.
  • People with elevated liver enzyme levels (AST) more than three times the normal upper limit.
  • People with liver cirrhosis (serious scarring of the liver).
  • People who drink more than 20 grams of alcohol per day (for women) or more than 30 grams per day (for men).
  • People who are pregnant, breastfeeding, or planning to become pregnant during the study.
  • People who currently have haemorrhoids or piles that are causing rectal bleeding when passing a stool.
  • People who are currently using steroid medications taken by mouth or injection (systemic steroids).
  • People who are currently using insulin.
  • People who are currently using weight-loss medications, including GLP-1 receptor agonist injections or tablets, orlistat, or phentermine.
  • People who have used antibiotics, prebiotics, probiotics, vitamin C supplements, or traditional Chinese medicine within the past month.
  • People with thyroid disease that is not well controlled.
  • People for whom there are concerns about being able to follow the study requirements, such as those with dementia, substance use issues, a history of missing appointments, or family concerns about taking part.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +65-6222 3322

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Not Yet Recruiting
Phase
Not Applicable
Sponsor
Singapore General Hospital
Registry
ClinicalTrials.gov
Start date
1 August 2026
Est. completion
1 December 2027

Where this trial is recruiting

🇸🇬 Singapore

Primary endpoints

Change in gut microbiome composition following durian consumption; Change in plasma metabolomic profile following durian consumption; Change in glucose metrics during and after durian consumption

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov